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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13C
All Species:
13.64
Human Site:
S3348
Identified Species:
37.5
UniProt:
Q709C8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q709C8
NP_001018098.1
3753
422390
S3348
L
G
S
G
G
E
E
S
D
K
E
K
Q
E
M
Chimpanzee
Pan troglodytes
XP_510458
3836
431033
S3431
L
G
S
G
G
E
E
S
D
K
E
K
Q
E
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851912
3629
408076
M3269
F
M
V
L
I
Q
E
M
A
L
K
V
D
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX70
3748
420070
S3343
L
G
S
G
G
E
E
S
D
K
E
K
Q
E
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511058
3801
426177
S3396
L
G
S
G
G
E
E
S
D
K
E
K
Q
E
M
Chicken
Gallus gallus
XP_001233000
3758
422392
A3352
S
L
A
S
G
A
E
A
S
D
K
G
E
E
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922767
3699
412330
D3322
L
S
L
G
S
S
G
D
E
S
E
Q
G
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192977
2470
271032
F2114
T
N
V
D
D
V
I
F
K
L
G
F
F
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07878
3144
357831
M2788
Y
Y
V
H
M
F
A
M
T
L
G
N
I
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
87
N.A.
86.4
N.A.
N.A.
77.2
68.7
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
97.4
N.A.
92
N.A.
93.3
N.A.
N.A.
87.6
82.9
N.A.
76.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
100
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
N.A.
N.A.
100
53.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
12
12
12
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
0
0
12
45
12
0
0
12
12
0
% D
% Glu:
0
0
0
0
0
45
67
0
12
0
56
0
12
67
12
% E
% Phe:
12
0
0
0
0
12
0
12
0
0
0
12
12
0
0
% F
% Gly:
0
45
0
56
56
0
12
0
0
0
23
12
12
0
12
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
12
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
45
23
45
0
0
0
% K
% Leu:
56
12
12
12
0
0
0
0
0
34
0
0
0
0
0
% L
% Met:
0
12
0
0
12
0
0
23
0
0
0
0
0
0
67
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
12
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
12
45
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
12
12
45
12
12
12
0
45
12
12
0
0
0
0
0
% S
% Thr:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% T
% Val:
0
0
34
0
0
12
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _